Variation in the sequence of a mitochondrial nadh dehydrogenase I gene fragment among six natural populations of Schistosoma japonicum from China

Sørensen, E.; Drew, A. c.; Brindley, P. J.; Bøgh, H. O.; Gasser, R. B.; Qian, B. Z.; Chiping, Q.; McManus, D. P.

Variation in the sequence of a mitochondrial nadh dehydrogenase I gene fragment among six natural populations of Schistosoma japonicum from China

Date

1998-12-01

Authors

Abstract

The present study investigated the level of genetic variation among Schistosoma japonicum populations of different geographical origins from mainland China. Polymerase chain reaction-based methods were employed to determine the sequence for a subunit of the mitochondrial NADH dehydrogenase I gene for populations from Zhejiang, Anhui, Jiangxi, Hunan, Hubei and Sichuan. No variation was detectable in the NADH dehydrogenase I sequence within populations from Zhejiang and Hubei, whereas sequence variation of 0.2% was detected within populations from Anhui, Jiangxi, Hunan and Sichuan. Pairwise comparison of the sequences representing the six different populations revealed genetic differences ranging from 0 to 0.6%. Copyright (C) 1998 Australian Society for Parasitology.