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Mechanisms of accelerated immune-mediated diabetes resulting from islet β cell expression of a Fas ligand transgene

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Authors

Silva, Diego
Petrovsky, Nikolai
Socha, L
Slattery, Robyn
Gatenby, Paul
Charlton, Brett

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American Association of Immunologists

Abstract

Nonobese diabetic (NOD) mice transgenic for Fas ligand (FasL) on islet β cells (HIPFasL mice) exhibit an accelerated diabetes distinct from the normal autoimmune diabetes of NOD mice. This study was undertaken to define the mechanism underlying accelerat

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Journal of Immunology

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DOI

Restricted until

2037-12-31