Total synthesis of uniflorine A, casuarine, australine, 3-epi-australine, and 3,7-di-epi-australine from a common precursor
Abstract
(Chemical Equation Presented) Aflexible method for the diastereoselective total synthesis of the pyrrolizidine alkaloids uniflorine A, casuarine, australine, and 3-epi-australine and the unnatural epimer 3,7-di-epi-australine from a common chiral 2,5-dihydropyrrole precursor is described.
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Ritthiwigrom , T , Willis , A C & Pyne , S G 2010 , ' Total synthesis of uniflorine A, casuarine, australine, 3-epi-australine, and 3,7-di-epi-australine from a common precursor ' , Journal of Organic Chemistry , vol. 75 , no. 3 , pp. 815-824 . https://doi.org/10.1021/jo902355p
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Journal of Organic Chemistry