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Fat Aussie - A new alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis

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Date

2006

Authors

Arsov, Todor
Silva, Diego
O'Bryan, Moira K
Sainsbury, Amanda
Lee, Nicola J
Kennedy, Claire L
Manji, Shehnaaz
Nelms, Keats
Liu, Conan
Garcia De Vinuesa, Maria Carola

Journal Title

Journal ISSN

Volume Title

Publisher

Endocrine Society (USA)

Abstract

Mutations in the human ALMS1 gene are responsible for Alström syndrome, a disorder in which key metabolic and endocrinological features include childhood-onset obesity, metabolic syndrome, and diabetes, as well as infertility. ALMS1 localizes to the basa

Description

Keywords

Keywords: protein fos; ALMS1 gene; Alstrom syndrome; animal cell; animal experiment; animal model; animal tissue; article; audiology; body composition; body weight; cell hyperplasia; cell loss; controlled study; diabetes mellitus; female; fertility; food intake; ge

Citation

URI

http://hdl.handle.net/1885/84999

Collections

Open Access Research

Source

Molecular Endocrinology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1210/me.2005-0494

Restricted until

2037-12-31

Downloads

File
Description
01_Arsov_Fat_Aussie_-_A_new_alstrom_2006.pdf (887.36 KB)

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