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Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

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Authors

Arndt, Verena
Dick, Nikolaus
Tawo, Riga
Dreiseidler, Michael
Wenzel, Daniela
Hesse, Michael
Furst, Dieter O.
Saftig, Paul
Saint, Robert
Fleischmann, Bernd K.

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Cell Press

Abstract

How are biological structures maintained in a cellular environment that constantly threatens protein integrity? Here we elucidate proteostasis mechanisms affecting the Z disk, a protein assembly essential for actin anchoring in striated muscles, which is

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Current Biology

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2037-12-31