Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection

Tötemeyer, Sabine; Foster, Neil; Kaiser, Pete; Maskell, Duncan J.; Bryant, Clare E.

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Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection

Date

2003

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Abstract

Here, we have investigated the mRNA expression of Toll-like receptor 2 (TLR-2), TLR-4, and MD-2 in spleens and livers of C3H/HeN mice (carrying wild-type TLR-4) and C3H/HeJ mice (carrying mutated TLR-4) in response to Salmonella infection. During Salmonella infections, TLR-4 is activated, leading to increased TLR-2 and decreased TLR-4 expression.

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https://dspace-test.anu.edu.au/handle/1885/733737674

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DevOps Pure Testing

Source

Infection and Immunity

Type

Article

DOI

10.1128/IAI.71.11.6653-6657.2003

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Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection

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