Test environment running 7.6.6

Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

IDENTIFICATION OF PLACENTAL PROTEIN 14 AS AN IMMUNOSUPPRESSIVE FACTOR IN HUMAN REPRODUCTION

Thumbnail Image

Date

1987-03-14

Authors

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Extracts of human decidual tissue obtained in the first trimester of pregnancy showed potent suppressive activity in mixed lymphocyte cultures. These extracts contained substantial amounts of the decidual protein PP14. Purified PP14 also exhibited in vitro immunosuppressive activity, and such activity in decidual extract and purified PP14 preparations was removed by treatment with a monoclonal anti-PP14 antibody-based immunoadsorbent. PP14 was present in seminal plasma, which also exhibited immunosuppressive activity that could be reduced, but not removed, by the immunoadsorbent. PP14 may be an important immunomodulator in the human reproductive system.

Description

Keywords

Citation

URI

https://dspace-test.anu.edu.au/handle/1885/733743360

Collections

DevOps Pure Testing

Source

The Lancet

Type

Article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/S0140-6736(87)90235-2

Restricted until

DSpace software copyright © 2002-2026 LYRASIS