Alkylations and hydroxymethylations of pyrazines via green minisci-type reactions

Bohman, Bjorn; Berntsson, Benjamin; Dixon, Ruby C.M.; Stewart, Craig D.; Barrow, Russell A.

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Alkylations and hydroxymethylations of pyrazines via green minisci-type reactions

Date

2014-06-06

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Abstract

A new general methodology utilizing Minisci-type chemistry has been developed that cleanly and efficiently prepares alkyl- and (hydroxymethyl) pyrazines. The new methods eliminate toxic catalysts and halogenated solvents, providing a greatly improved route to these natural products which are prevalent in many natural systems as bacterial volatiles, plant volatiles, and insect pheromones.

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https://dspace-test.anu.edu.au/handle/1885/733749266

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DevOps Pure Testing

Source

Organic Letters

Type

Article

DOI

10.1021/ol500776j

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Alkylations and hydroxymethylations of pyrazines via green minisci-type reactions

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