Leptin replacement improves cognitive development

Da Paz Filho, Gilberto; Babikian, Talin; Asarnow, Robert; Delibasi, T; Esposito, Karin; Erol, Halil Kutlu; Wong, Ma-Li; Licinio, Julio

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Leptin replacement improves cognitive development

Date

2008

Authors

Da Paz Filho, Gilberto

Babikian, Talin

Asarnow, Robert

Delibasi, T

Esposito, Karin

Erol, Halil Kutlu

Wong, Ma-Li

Licinio, Julio

Publisher

Public Library of Science

Abstract

Background:Leptin changes brain structure, neuron excitability and synaptic plasticity. It also regulates the development and function of feeding circuits. However, the effects of leptin on neurocognitive development are unknown.Objective:To evaluate the