Structural characterization of piperidine alkaloids from Pandanus amaryllifolius by inverse-detected 2D NMR techniques

Nonato, Maribel G.; Garson, Mary J.; Truscott, Roger J.W.; Carver, John A.

Structural characterization of piperidine alkaloids from Pandanus amaryllifolius by inverse-detected 2D NMR techniques

Date

1993

Authors

Nonato, Maribel G.

Garson, Mary J.

Truscott, Roger J.W.

Carver, John A.

Abstract

Three novel piperidine alkaloids were isolated and identified from the leaves of Pandanus amaryllifolius. The structures of pandamarilactone-1, pandamarilactone-32 and pandamarilactone-31 were elucidated using 2D NMR techniques including inverse-detected Heteronuclear Multiple Bond Correlation (HMBC) and Heteronuclear Multiple Quantum Coherence (HMQC) spectroscopy. All of these piperidine alkaloids have a C9-N-C9 skeleton and could be derived biogenetically from 4-hydroxy-4-methylglutamic acid.