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Exocyclic bromination of N-substituted β- and γ-lactams

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Date

1990

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Abstract

Regioselective halogenation of the N-susbtituted lactams (3a)-(3d) affords the corresponding exocyclic bromides (4a)-(4d). The procedure provides a novel alternative route to N-(α-haloalkyl)-substituted lactams, which are of particular interest in the synthesis of β-lactam antibiotics.

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Citation

URI

https://dspace-test.anu.edu.au/handle/1885/733746374

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DevOps Pure Testing

Source

Tetrahedron Letters

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Article

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DOI

10.1016/S0040-4039(00)97425-2

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