Characterization of chemical isolates of caryopteris odorata

Abstract

The phytochemical investigation of the chloroform soluble fraction of Caryopteris odorata (Ham. ex Roxb.) led to the isolation of one new constituent namely; n-pentadecyl[3-(4- hydroxyphenyl)] propanoate (1). The compounds 2-ethyl-n-hexyl benzoate (2), 2-ethyl-n-hexyl trans-cinnamate (3) bis-dodecylbenzene-1,4-dicarboxylate (4) were reported synthetically but these have been isolated for the first time from a natural source. Similarly, the known constituent like trans-cinnamic acid (5) and cis-cinnamic acid (6), henicosanoic acid (7), methyl tricontanoate (8) and octacosanyl tricontanoate (9) were also obtained for the first time from this plant source. The structures of these compounds were determined by IR, HR-MS, 1H-NMR, 13C-NMR spectroscopy and by comparison with the published data of the closely related compounds [8-15]. These isolates were screened for their antioxidant, anti-urease and anti-tyrosinase activities and results revealed that n-Pentadecyl [3-(4-hydroxyphenyl)] propanoate (1) exhibits good antioxidant potential with low to zero enzyme inhibition activities. Show more