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Two modes of β-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3

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Date

2010

Authors

Mirza, Shamaruh
Chen, Jinglong
Wen, Bin
Ewans, Cameron
Dai, Jin
Murphy, James M
Young, Ian

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Biochemistry and Molecular Biology Inc

Abstract

The cytokine interleukin-3 (IL-3) is a critical regulator of inflammation and immune responses in mammals. IL-3 exerts its effects on target cells via receptors comprising an IL-3-specific α-subunit and common β-subunit (βc; shared with IL-5 and granul

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/34064

Collections

Open Access Research

Source

Journal of Biological Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1074/jbc.M110.117465

Restricted until

2037-12-31

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Description
01_Mirza_Two_modes_of_β-receptor_2010.pdf (1.89 MB)

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