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Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, ε, θ and β reveals a highly flexible arrangement of the proofreading domain

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Ozawa, Kiyoshi
Horan, Nicholas P
Robinson, Andrew
Yagi, Hiromasa
Hill, Flynn R
Jergic, Slobodan
Xu, Zhi-Qiang
Loscha, Karin
Li, Nan
Tehei, Moeava

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Oxford University Press

Abstract

A complex of the three (αεθ) core subunits and the β2 sliding clamp is responsible for DNA synthesis by Pol III, the Escherichia coli chromosomal DNA replicase. The 1.7 Å crystal structure of a complex between the PHP domain of α (polymerase) and th

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Nucleic Acids Research

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2037-12-31