Metabolites of marine algae collected from Karachi-coasts of Arabian sea

Abstract

The ethanolic extracts of marine green, brown and red algae collected from Karachi coasts of Arabian Sea afforded a new enol-derivative of N-acylsphingosine named as coelarthenol (1) from Coelarthrum muelleri, two new glucose-derivatives named: botryenal (2) and botryenol (3) from Botryocladia leptopoda, α-tocopherol quinone (4) from Codium iyengarii, β-sitosterol and hexadecanoic acid from Stokeyia indica. The known constituents (4, β-sitosterol and hexadecanoic acid) have not been reported so far from their corresponding sources and the structures were determined through spectroscopic methods, whereas, the structures of new constituents (1-3) were elucidated with the aid of selective HMBC experiments. The phytotoxicity of 4 was also monitored. Show more