Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

Dumez, Jean Nicolas; Milani, Jonas; Vuichoud, Basile; Bornet, Aurélien; Lalande-Martin, Julie; Tea, Illa; Yon, Maxime; Maucourt, Mickaël; Deborde, Catherine; Moing, Annick; Frydman, Lucio; Bodenhausen, Geoffrey; Jannin, Sami; Giraudeau, Patrick

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Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

Date

2015-09-07

Authors

Lalande-Martin, Julie

Abstract

Natural abundance 13C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.

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https://dspace-test.anu.edu.au/handle/1885/733715719

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DevOps Pure Testing

Source

The Analyst

Type

Article

DOI

10.1039/c5an01203a

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Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

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