The Stereochemistry of some α,β-Di-(2-thienyl)Acrylonitriles and β,β′-Di-(2- thienyl)-α,α′-(2, 5-thiophen)Diacrylonitriles

Abstract

It has been shown that condensation of thiophen-2-aldehyde with 2-thienyl- acetonitrile gives trans-α β-di-(2-thienyl)acrylonitrile; but condensation of thiophen- 2-aldehyde with 2-thienylacetic acid yields cis-α,β-di-(2-thienyl)acrylic acid. Similarly, condensation of thiophen-2-aldehydes with 2, 5-biscyanomethylthiophen gave trans-trans -β,β′-di-(2-thienyl)-α,α′-(2, 5-thiophen)diacrylonitriles; but condensation with thiophen-2, 5-diacetic acid gave cis-cis-β,β′-di-(2-thieny1)-α,α′-(2, 5-thio-phen)diacrylic acids. Show more