Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection

Riera, LudovicoGariglio, MarisaValente, GuidoMullbacher, ArnoMuseteanu, CrisanLandolfo, SantoSimon, Markus M2015-12-080014-2980http://hdl.handle.net/1885/33974The course of mouse cytomegalovirus (MCMV) infection was compared between wild-type and mutant C57BL/6 (B6) mice deficient in either RAG-2, perforin, granzyme A, granzyme B or combinations thereof at two time points post infection (p.i.). At day 15 p.i.,Keywords: CD8 antigen; granzyme A; granzyme B; perforin; animal experiment; animal model; animal tissue; article; controlled study; Cytomegalovirus; cytomegalovirus infection; disease course; inflammation; lung; mouse; natural killer cell; nonhuman; pathology; prio Granzyme; Murine cytomegalovirus replication; Perforin; RAG-2Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection200010.1002/(SICI)1521-4141(200005)30:5<1350::AID-IMMU1350>3.0.CO;2-J2015-12-08