Extracellular vesicle lipids in cancer immunoevasion

Chen, Siyu; Iannotta, Dalila; O'Mara, Megan L.; Goncalves, Jenifer Pendiuk; Wolfram, Joy

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Extracellular vesicle lipids in cancer immunoevasion

Date

2023

Authors

Chen, Siyu

Iannotta, Dalila

O'Mara, Megan L.

Goncalves, Jenifer Pendiuk

Wolfram, Joy

Abstract

Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.