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Pentobarbital Modulates gamma-Aminobutyric Acid-Activated Single-Channel Conductance in Rat Cultured Hippocampal Neurons

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Date

2000

Authors

Eghbali, Mansoureh
Gage, Peter
Birnir, Bryndis

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Pharmacology and Experimental Therapeutics

Abstract

We examined the effect of a range of pentobarbital concentrations on 0.5 μM γ-aminobutyric acid (GABA)-activated channels (10 ± 1 pS) in inside-out or outside-out patches from rat cultured hippocampal neurons. The conductance increased from 12 ± 4 to

Description

Keywords

Keywords: 4 aminobutyric acid; diazepam; ion channel; pentobarbital; animal cell; article; cell membrane transport; channel gating; concentration response; controlled study; drug antagonism; hippocampus; nerve cell membrane conductance; neuromodulation; newborn; no

Citation

URI

http://hdl.handle.net/1885/90236

Collections

Open Access Research

Source

Molecular Pharmacology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until

2037-12-31

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Description
01_Eghbali_Pentobarbital_Modulates_2000.pdf (161.05 KB)

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