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Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9- O -sulfate from an Indonesian Aaptos sp. marine sponge

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Date

2004

Authors

Herlt, Anthony
Mander, Lewis
Rombang, Wilson
Rumampuk, Rymond
Soemitro, Soetijoso
Steglich, Wolfgang
Tarigan, Ponis
von Nussbaum, Franz

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.

Description

Keywords

Keywords: aaptamine; bisnoraaptamine 9 o sulfate; unclassified drug; analytic method; article; comparative study; high performance liquid chromatography; Indonesia; isolation procedure; nonhuman; priority journal; spectroscopy; sponge (Porifera); synthesis; Aaptos Aaptos; Bisdemethylaaptamine; Sulfated aaptamines

Citation

URI

http://hdl.handle.net/1885/77889

Collections

Open Access Research

Source

Tetrahedron

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.tet.2004.05.068

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