Triterpenoid saponin from the bark of Guaiacum officinale L.

Abstract

A new triterpenoid saponin, guaianin R (1) was isolated from the n-BuOH extract of bark of Guaiacum officinale L. It was characterized as akebonic acid-3-O-[α-L-rhamnopyranosyl-(1 → 3)-β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside]-28-O-[β-D-glucopyranosyl]-ester. The structure was established with the help of a comparative study of 1D and 2D 1H-13C NMR methods. A number of other saponins were isolated and reported from the same species. Show more