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Quadrupole mass filter spectrum control using pulse width modulation

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Pulse width, or duty cycle, modulation during mass sweeping in a rectangular-excited quadrupole mass filter is shown to be of benefit in offsetting mass discriminatory effects and in implementing novel scan techniques. In addition by pulse with modification over spectral windows it is demonstrated how portions of spectra can be enhanced or suppressed, enabling selected peaks to be intensified and permitting in situ mass marking.

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International Journal of Mass Spectrometry and Ion Physics

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