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The molecular epidemiology of Echinococcus granulosus and cystic hydatid disease

dc.contributor.authorMcManus, D. P.en
dc.date.accessioned2025-03-22T18:29:21Z
dc.date.available2025-03-22T18:29:21Z
dc.date.issued2002en
dc.description.abstractIt is now generally recognized that the dog tapeworm Echinococcus granulosus, the cause of cystic hydatid disease, exhibits substantial genetic diversity. This variability has important implications for the design and development of vaccines, diagnostic reagents and drugs effective against this parasite. The paper describes various deoxyribonucleic acid-based approaches that have been used for accurate identification of these genetic variants and their application in molecular epidemiological surveys of cystic hydatid disease in different geographical settings.en
dc.description.sponsorshipAcknowledeements I thank my many collaborators who have either helped in the DNA analysis or who have kindly provided hydatid materials for study over a period of 20 years. I also acknowledge the National Health and Medical Research Council of Australia for continual financial support. I am indepted to Douglas Barker, who was a great inspiration and source of information throughout many of the early studies described in this review.en
dc.description.statustrueen
dc.identifier.otherScopus:0036334509en
dc.identifier.otherPubMed:12061336en
dc.identifier.urihttps://dspace-test.anu.edu.au/handle/1885/733730215
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=0036334509&partnerID=8YFLogxKen
dc.language.isoEnglishen
dc.sourceTransactions of the Royal Society of Tropical Medicine and Hygieneen
dc.subjectCystic hydatidosisen
dc.subjectEchinococcus granulosusen
dc.subjectEpidemiologyen
dc.subjectGenetic diversityen
dc.subjectHydatidosisen
dc.titleThe molecular epidemiology of Echinococcus granulosus and cystic hydatid diseaseen
dc.typeArticleen
local.bibliographicCitation.startpageS151en
local.contributor.affiliationMcManus, D. P.; University of Queenslanden
local.identifier.citationvolume96en
local.identifier.doi10.1016/s0035-9203(02)90068-4en
local.identifier.pureb4e8ca46-846a-41f1-a73e-3265e82f98been
local.type.statusPublisheden

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