CD127+ CCR5 + CD38+++ CD4+ Th1 effector cells are an early component of the primary immune response to vaccinia virus and precede development of interleukin-2+ memory CD4+ T cells
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Date
Authors
Zaunders, John J
Dyer, Wayne B.
Munier, Mee Ling
Ip, Susanna
Liu, Jie
Amyes, Elisabeth
Rawlinson, William
De Rose, Robert
Kent, Stephen J
Sullivan, John S.
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American Society for Microbiology
Abstract
The stages of development of human antigen-specific CD4+ T cells responding to viral infection and their differentiation into long-term memory cells are not well understood. The inoculation of healthy adults with vaccinia virus presents an opportunity to
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Journal of Virology
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2037-12-31