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A chemoenzymatic synthesis of the anti-influenza agent Tamiflu

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Date

2008

Authors

Matveenko, Maria
Willis, Anthony
Banwell, Martin

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

The anti-influenza drug Tamiflu® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.

Description

Keywords

Keywords: bromobenzene; catechol derivative; cis 1,2 dihydrocatechol; oseltamivir; unclassified drug; article; crystal structure; drug structure; drug synthesis; enantioselectivity Acylaziridine; Anti-influenza; cis-1,2-Dihydrocatechol; Synthesis; Tamiflu®

Citation

URI

http://hdl.handle.net/1885/52540

Collections

Open Access Research

Source

Tetrahedron Letters

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.tetlet.2008.09.130

Restricted until

2037-12-31

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Description
01_Matveenko_A_chemoenzymatic_synthesis_of_2008.pdf (283.67 KB)

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