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C. elegans RNA-dependent RNA polymerases rrf-1 and ego-1 silence Drosophila transgenes by differing mechanisms

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Authors

Duan, Guowen (Tony)
Saint, Robert B
Helliwell, Christopher Andrew
Behm, Carolyn
Wang, Ming-Bo
Waterhouse, Peter M.
Gordon, Karl H J

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Birkhauser Verlag

Abstract

Drosophila possesses the core gene silencing machinery but, like all insects, lacks the canonical RNA-dependent RNA polymerases (RdRps) that in C. elegans either trigger or enhance two major small RNA-dependent gene silencing pathways. Introduction of two

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Cellular and Molecular Life Sciences

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Restricted until

2037-12-31