Oxazolines as Directing Agents in the Nucleophilic Addition to Naphthalenes

Scott, Andrew

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Oxazolines as Directing Agents in the Nucleophilic Addition to Naphthalenes

Date

2003

Authors

Scott, Andrew

Publisher

CSIRO Publishing

Abstract

Oxazolines are ideal chiral auxiliaries to effect high-yielding diastereoselective transformations. These compounds activate the naphthalene π-system to nucleophilic addition. Potential applications include the total synthesis of (-)-podophyllotoxin and