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New bioactive diterpenoid from Euphorbia decipiens

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Date

2002-09-01

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Abstract

One new diterpene ester with a tricyclic lathyrane-or myrsinol-type skeleton has been isolated from Euphorbia decipiens Boiss. & Buhse. In addition to one new, the known constituents β-amyrin, β-amyrin acetate, methyl (2,4-dihydroxy-3-formyl-6-methoxy) phenyl ketone (2), and 1,1-bis (2,6-dihydroxy-3-acetyl-4-methoxyphenyl) methane (3) have been isolated from the same source. The structure elucidation of the isolated compounds was based primarily on 1D and 2D-NMR analysis, including COSY, HMQC, HMBC and NOESY correlations. Compound 1 showed inhibitory activity against prolyl endopeptidase, and also analgesic activity.

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Keywords

Diterpene Esters, Euphorbia decipiens, Prolyl Endopeptidase

Citation

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https://dspace-test.anu.edu.au/handle/1885/733728069

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DevOps Pure Testing

Source

Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

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DOI

10.1515/znb-2002-0913

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