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Paramagnetic labelling of proteins and oligonucleotides for NMR

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Authors

Su, Xun-Cheng
Otting, Gottfried

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Publisher

Kluwer Academic Publishers

Abstract

Paramagnetic effects offer a rich source of long-range structural restraints. Here we review current methods for site-specific tagging of proteins and oligonucleotides with paramagnetic molecules. The paramagnetic tags include nitroxide radicals and metal chelators. Particular emphasis is placed on tags suitable for site-specific and rigid attachment of lanthanide ions to macromolecules.

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Source

Journal of Biomolecular NMR

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Restricted until

2037-12-31