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Carboxymethylated-κ-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation

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Authors

Carver, John
Duggan, Peter J
Ecroyd, Heath
Liu, Yanqin
Meyer, Adam G.
Tranberg, Elisabet

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Publisher

Pergamon-Elsevier Ltd

Abstract

Reduced and carboxymethylated-κ-casein (RCM-κ-CN) is a milk-derived amyloidogenic protein that readily undergoes nucleation-dependent aggregation and amyloid fibril formation via a similar pathway to disease-specific amyloidogenic peptides like amyloid

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Source

Bioorganic and Medicinal Chemistry

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Restricted until

2037-12-31