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Detection of trophoblast-like cells in maternal blood using specific monoclonal antibodies

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Date

1987

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Abstract

Mouse monoclonal antibodies reacting against membrane antigens expressed on syncytiotrophoblast (McAb H315), villous cytotrophoblast (McAb 18B/A5) and placental-type alkaline phosphatase-producing cells (McAb H317) were used in conjunction with flow cytometry to detect placental cells in the maternal circulation. H315 and H317-positive cells were found in uterine veins and peripheral blood of pregnant women, while cells reacting with McAb 18B/A5 were either absent or present in very low numbers.

Description

Keywords

maternal circulation, monoclonal antibodies, placental syncytiotrophoblast, trophoblast antigens

Citation

URI

https://dspace-test.anu.edu.au/handle/1885/733740982

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DevOps Pure Testing

Source

Journal of Reproductive Immunology

Type

Article

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DOI

10.1016/0165-0378(87)90006-4

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